References: (click on chapter name to view references)

Part 1. Introduction

Section 1. General Considerations
Chapter 1 The Epidemiology and Burden of Skin Disease
Chapter 2 Evidence-Based Dermatology
Chapter 3 Public Health in Dermatology

Section 2. Approach to Dermatologic Diagnosis
Chapter 4 Structure of Skin Lesions and Fundamentals of Clinical Diagnosis
Chapter 5 Diagnostic Procedures and Devices
Chapter 6 Basic Pathologic Reactions of the Skin

Section 3. Overview of Biology, Development, and Structure of Skin
Chapter 7 Development and Structure of Skin
Chapter 8 Genetics in Relation to the Skin
Chapter 9 Basic Science Approaches to the Pathophysiology of Skin Disease

Part 2. Disorders Presenting in Skin and Mucous Membranes

Section 4. Inflammatory Disorders Based on T-Cell Reactivity and Dysregulation
Chapter 10 Innate and Adaptive Immunity in the Skin
Chapter 11 Cytokines
Chapter 12 Chemokines
Chapter 13 Allergic Contact Dermatitis
Chapter 14 Atopic Dermatitis (Atopic Eczema)
Chapter 15 Nummular Eczema and Lichen Simplex Chronicus/Prurigo Nodularis
Chapter 16 Vesicular Palmoplantar Eczema
Chapter 17 Autosensitization Dermatitis
Chapter 18 Psoriasis
Chapter 19 Psoriatic Arthritis
Chapter 20 Reactive Arthritis
Chapter 21 Pustular Eruptions of Palms and Soles
Chapter 22 Seborrheic Dermatitis
Chapter 23 Exfoliative Dermatitis
Chapter 24 Pityriasis Rubra Pilaris
Chapter 25 Parapsoriasis and Pityriasis Lichenoides
Chapter 26 Lichen Planus
Chapter 27 Lichen Nitidus
Chapter 28 Graft-versus-Host Disease
Chapter 29 Skin Disease in Acute and Chronic Immunosuppression

Section 5. Inflammatory Diseases Based on Neutrophils and Eosinophils
Chapter 30 Regulation of the Production and Activation of Neutrophils and Eosinophils
Chapter 31 Acute Febrile Neutrophilic Dermatosis (Sweet Syndrome)
Chapter 32 Pyoderma Gangrenosum
Chapter 33 Granuloma Faciale
Chapter 34 Sub-Corneal Pustular Dermatosis (Sneddon-Wilkinson Disease)
Chapter 35 Eosinophils in Cutaneous Diseases

Section 6. Inflammatory Diseases Based on Abnormal Humoral Reactivity and Other Inflammatory Diseases
Chapter 36 Humoral Immunity and Complement
Chapter 37 Urticaria and Angioedema
Chapter 38 Erythema Multiforme
Chapter 39 Epidermal Necrolysis (Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis)
Chapter 40 Cutaneous Reactions to Drugs
Chapter 41 Pityriasis Rosea
Chapter 42 Erythema Annulare Centrifugum and Other Figurate Erythemas
Chapter 43 Granuloma Annulare

Section 7. Disorders of Epidermal Differentiation and Keratinization
Chapter 44 Epidermal Growth and Differentiation
Chapter 45 Skin as an Organ of Protection
Chapter 46 Irritant Contact Dermatitis
Chapter 47 The Ichthyoses
Chapter 48 Inherited Keratodermas of Palms and Soles
Chapter 49 Acantholytic Disorders of the Skin: Darier-White Disease, Acrokeratosis                    Verruciformis, Grover Disease, and Hailey-Hailey Disease
Chapter 50 Porokeratosis

Section 8. Disorders of Epidermal and Dermal-Epidermal Cohesion and Vesicular and Bullous Disorders
Chapter 51 Epidermal and Epidermal-Dermal Cohesion
Chapter 52 Pemphigus
Chapter 53 Paraneoplastic Pemphigus
Chapter 54 Bullous Pemphigoid
Chapter 55 Cicatricial Pemphigoid
Chapter 56 Linear Immunoglobulin A Dermatosis and Chronic Bullous Disease of Childhood
Chapter 57 Pemphigoid Gestationis (Herpes Gestationis)
Chapter 58 Epidermolysis Bullosa Acquisita
Chapter 59 Dermatitis Herpetiformis
Chapter 60 Inherited Epidermolysis Bullosa

Section 9. Disorders of the Dermal Connective Tissue
Chapter 61 Collagen, Elastic Fibers, and Extracellular Matrix of the Dermis
Chapter 62 Morphea
Chapter 63 Lichen Sclerosus
Chapter 64 Dermal Hypertrophies
Chapter 65 Anetoderma and Other Atrophic Disorders of the Skin
Chapter 66 Constricting Bands (Ainhum and Pseudoainhum)
Chapter 67 Acquired Perforating Disorders

Section 10. Disorders of Subcutaneous Tissue
Chapter 68 Panniculitis
Chapter 69 Lipodystrophy

Section 11. Disorders of Melanocytes
Chapter 70 Biology of Melanocytes
Chapter 71 Albinism and Other Genetic Disorders of Pigmentation
Chapter 72 Vitiligo
Chapter 73 Hypomelanoses and Hypermelanoses

Section 12. Disorders of the Oral and Genital Integument
Chapter 74 Biology and Pathology of the Oral Cavity
Chapter 75 Diseases and Disorders of the Male Genitalia
Chapter 76 Diseases and Disorders of the Female Genitalia

Part 3. Disorders of the Skin Appendages

Section 13. Disorders of the Sebaceous Glands
Chapter 77 Biology of Sebaceous Glands
Chapter 78 Acne Vulgaris and Acneiform Eruptions
Chapter 79 Rosacea
Chapter 80 Perioral Dermatitis

Section 14. Disorders of the Eccrine and Apocrine Glands
Chapter 81 Biology of Eccrine, Apocrine, and Apoeccrine Sweat Glands
Chapter 82 Disorders of the Eccrine Sweat Glands and Sweating
Chapter 83 Disorders of the Apocrine Sweat Glands

Section 15. Disorders of the Hair and Nails
Chapter 84 Biology of Hair Follicles
Chapter 85 Keratosis Pilaris and Other Inflammatory Follicular Keratotic Syndromes
Chapter 86 Hair Growth Disorders
Chapter 87 Biology of Nails and Nail Disorders

Part 4. Disorders Due to the Environment

Section 16. Disorders Due to Ultraviolet Radiation
Chapter 88 Fundamentals of Cutaneous Photobiology and Photoimmunology
Chapter 89 Acute and Chronic Effects of Ultraviolet Radiation on the Skin
Chapter 90 Abnormal Responses to Ultraviolet Radiation: Idiopathic, Probably Immunologic,                   and Photo-Exacerbated
Chapter 91 Abnormal Responses to Ultraviolet Radiation: Photosensitivity Induced by                   Exogenous Agents

Section 17. Skin Changes Due to Other Physical and Chemical Factors
Chapter 92 Thermoregulation
Chapter 93 Cold Injuries
Chapter 94 Thermal Injuries
Chapter 95 Radiobiology and Radiation Effects
Chapter 96 Skin Problems in Amputees and Ostomates
Chapter 97 Corns and Calluses
Chapter 98 Sports Dermatology
Chapter 99 Decubitus (Pressure) Ulcers
Chapter 100 Body Art

Part 5. Neurocutaneous and Psychocutaneous Aspects of Skin Disease

Section 18. Neurocutaneous and Psychocutaneous Skin Disease
Chapter 101 Neurobiology of the Skin
Chapter 102 Pathophysiology and Clinical Aspects of Pruritus
Chapter 103 Psychocutaneous Diseases
Chapter 104 Cutaneous Manifestations of Drug Abuse
Chapter 105 Skin Signs of Physical Abuse

Part 6. Skin Changes across the Span of Life

Section 19. From Birth to Old Age
Chapter 106 Neonatal, Pediatric, and Adolescent Dermatology
Chapter 107 Skin Changes and Diseases in Pregnancy
Chapter 108 Aging of Skin

Part 7. Neoplasia

Section 20. Carcinogenesis
Chapter 109 Genome Instability, DNA Repair, and Cancer
Chapter 110 Carcinogenesis: Chemical
Chapter 111 Oncogenes, Tumor Suppressor Genes, and Viral Carcinogenesis
Chapter 112 Carcinogenesis: Ultraviolet Radiation

Section 21. Epidermal and Appendageal Tumors
Chapter 113 Epithelial Precancerous Lesions
Chapter 114 Squamous Cell Carcinoma
Chapter 115 Basal Cell Carcinoma
Chapter 116 Basal Cell Nevus Syndrome
Chapter 117 Keratoacanthoma
Chapter 118 Benign Epithelial Tumors, Hamartomas, and Hyperplasias
Chapter 119 Appendage Tumors and Hamartomas of the Skin
Chapter 120 Merkel Cell Carcinoma
Chapter 121 Mammary and Extramammary Paget Disease

Section 22. Melanocytic Tumors
Chapter 122 Benign Neoplasias and Hyperplasias of Melanocytes
Chapter 123 Atypical Melanocytic Nevi
Chapter 124 Cutaneous Melanoma

Section 23. Tumors and Hyperplasias of the Dermis and Subcutaneous Fat
Chapter 125 Malignant Fibrous Tumors of the Dermis
Chapter 126 Vascular Tumors
Chapter 127 Neoplasias and Hyperplasias of Muscular and Neural Origin
Chapter 128 Kaposi Sarcoma
Chapter 129 Neoplasms of Subcutaneous Fat

Part 8. The Skin in Systemic Disease

Section 24. Skin in Nutritional, Metabolic, and Heritable Disease
Chapter 130 Cutaneous Changes in Nutritional Disease
Chapter 131 Cutaneous Changes in Errors of Amino Acid Metabolism
Chapter 132 The Porphyrias
Chapter 133 Amyloidosis and the Skin
Chapter 134 Systemic Autoinflammatory Diseases
Chapter 135 Xanthomatoses and Lipoprotein Disorders
Chapter 136 Fabry Disease
Chapter 137 Lipoid Proteinosis
Chapter 138 Cutaneous Mineralization and Ossification
Chapter 139 Heritable Disorders of Connective Tissue with Skin Changes
Chapter 140 Hereditary Disorders of Genome Instability and DNA Repair
Chapter 141 Tuberous Sclerosis Complex
Chapter 142 The Neurofibromatoses
Chapter 143 Ectodermal Dysplasias
Chapter 144 Genetic Immunodeficiency Diseases

Section 25. Skin Manifestations of Bone Marrow or Blood Chemistry Disorders
Chapter 145 Hematologic Diseases
Chapter 146 Cutaneous Lymphoma
Chapter 147 Inflammatory Diseases that Simulate Lymphomas: Cutaneous Pseudolymphomas
Chapter 148 Langerhans Cell Histiocytosis
Chapter 149 Non–Langerhans Cell Histiocytosis
Chapter 150 Biology of Mast Cells and the Mastocytosis Syndromes

Section 26. Skin Manifestations of Internal Organ Disorders
Chapter 151 The Skin and Disorders of the Alimentary Tract, the Hepatobiliary System, Kidney,                     and Cardiopulmonary System
Chapter 152 Diabetes Mellitus and Other Endocrine Diseases
Chapter 153 Sarcoidosis
Chapter 154 Cutaneous Manifestations of Internal Malignant Disease: Cutaneous                     Paraneoplastic Syndromes

Section 27. The Skin in Vascular and Connective Tissue and Other Autoimmune Disorders
Chapter 155 Mechanisms of Autoimmune Disease
Chapter 156 Lupus Erythematosus
Chapter 157 Dermatomyositis
Chapter 158 Scleroderma (Systemic Sclerosis)
Chapter 159 Scleredema and Scleromyxedema
Chapter 160 Relapsing Polychondritis
Chapter 161 Rheumatoid Arthritis, Rheumatic Fever, and Gout
Chapter 162 Sjögren Syndrome

Section 28. The Skin in Inflammatory and Other Vascular Disorders
Chapter 163 Endothelium in Inflammation and Angiogenesis
Chapter 164 Cutaneous Necrotizing Venulitis
Chapter 165 Systemic Necrotizing Vasculitis
Chapter 166 Erythema Elevatum Diutinum
Chapter 167 Adamantiades-Behçet Disease
Chapter 168 Kawasaki Syndrome
Chapter 169 Pigmented Purpuric Dermatoses
Chapter 170 Cryoglobulinemia and Cryofibrinogenemia
Chapter 171 Raynaud Phenomenon
Chapter 172 Malignant Atrophic Papulosis (Degos Disease)
Chapter 173 Vascular Malformations
Chapter 174 Cutaneous Changes in Peripheral Vascular Arterial Disease
Chapter 175 Cutaneous Changes in Venous and Lymphatic Insufficiency

Part 9. Disease due to Microbial Agents, Infestations, Bites, and Stings

Section 29. Bacterial Disease
Chapter 176 General Considerations of Bacterial Diseases
Chapter 177 Superficial Cutaneous Infections and Pyodermas
Chapter 178 Gram-Positive Infections Associated with Toxin Production
Chapter 179 Soft-Tissue Infections: Erysipelas, Cellulitis, Gangrenous Cellulitis, and                      Myonecrosis
Chapter 180 Gram-Negative Coccal and Bacillary Infections
Chapter 181 The Skin in Infective Endocarditis, Sepsis, Septic Shock, and Disseminated                      Intravascular Coagulation
Chapter 182 Bartonellosis
Chapter 183 Miscellaneous Bacterial Infections with Cutaneous Manifestations
Chapter 184 Tuberculosis and Infections with Atypical Mycobacteria
Chapter 185 Actinomycosis, Nocardiosis, and Actinomycetoma
Chapter 186 Leprosy
Chapter 187 Lyme Borreliosis

Section 30. Fungal Diseases
Chapter 188 Superficial Fungal Infection: Dermatophytosis, Onychomycosis, Tinea Nigra,                      Piedra
Chapter 189 Yeast Infections: Candidiasis and Tinea (Pityriasis) Versicolor
Chapter 190 Deep Fungal Infections

Section 31. Viral and Rickettsial Diseases
Chapter 191 Viral Diseases: General Considerations
Chapter 192 Exanthematous Viral Diseases
Chapter 193 Herpes Simplex
Chapter 194 Varicella and Herpes Zoster
Chapter 195 Poxvirus Infections
Chapter 196 Warts
Chapter 197 Human Retroviral Disease: Human T-Lymphotropic Viruses
Chapter 198 Cutaneous Manifestations of Human Immunodeficiency Virus Disease
Chapter 199 The Rickettsioses, Ehrlichioses, and Anaplasmoses

Section 32. Sexually Transmitted Diseases
Chapter 200 Syphilis
Chapter 201 Endemic (Non-Venereal) Treponematoses
Chapter 202 Chancroid
Chapter 203 Lymphogranuloma Venereum
Chapter 204 Granuloma Inguinale
Chapter 205 Gonorrhea and Other Venereal Diseases

Section 33. Infestations, Bites, and Stings
Chapter 206 Leishmaniasis and Other Protozoan Infections
Chapter 207 Helminthic Infections
Chapter 208 Scabies, Other Mites, and Pediculosis
Chapter 209 Bites and Stings of Terrestrial and Aquatic Life
Chapter 210 Arthropod Bites and Stings

Part 10. Occupational Skin Diseases and Skin Diseases Due to Biologic Warfare

Section 34. Occupational Skin Diseases
Chapter 211 Occupational Skin Diseases Due to Irritants and Allergens
Chapter 212 Occupational Noneczematous Skin Diseases Due to Biologic, Physical, and                      Chemical Agents

Section 35. The Skin in Bioterrorism and Biologic Warfare
Chapter 213 Cutaneous Manifestations of Biologic, Chemical, and Radiologic Terrorism Attacks

Part 11. Therapeutics

Section 36. Topical Therapy
Chapter 214 Principles of Topical Therapy
Chapter 215 Pharmacokinetics and Topical Applications of Drugs
Chapter 216 Topical Corticosteroids
Chapter 217 Topical Retinoids
Chapter 218 Topical Antibiotics
Chapter 219 Topical Antifungal Agents
Chapter 220 Topical and Intralesional Cytotoxic Agents
Chapter 221 Topical Immunomodulators
Chapter 222 Other Topical Medications
Chapter 223 Photoprotection and Sun Protective Agents
Chapter 224 Special Considerations for Topical Therapy of Ethnic Skin

Section 37. Systemic Therapy
Chapter 225 Systemic Glucocorticoids
Chapter 226 Dapsone
Chapter 227 Aminoquinolines
Chapter 228 Cytotoxic and Antimetabolic Agents
Chapter 229 Retinoids
Chapter 230 Antihistamines
Chapter 231 Antibiotics
Chapter 232 Antiviral Drugs
Chapter 233 Oral Antifungal Agents
Chapter 234 Immunosuppressive and Immunomodulatory Drugs
Chapter 235 Immunobiologicals, Cytokines, and Growth Factors in Dermatology
Chapter 236 Anti-Angiogenic Agents
Chapter 237 Drug Interactions

Section 38. Physical Treatments
Chapter 238 Therapeutic Photomedicine: Phototherapy
Chapter 239 Photochemotherapy and Photodynamic Therapy
Chapter 240 Lasers and Flashlamps in Dermatology
Chapter 241 Radiotherapy

Section 39. Complementary and Alternative Dermatology
Chapter 242 Complementary and Alternative Medicine in Dermatology

Section 40. Surgery in Dermatology
Chapter 243 Dermatologic Surgery: Introduction to Anatomy and Approach
Chapter 244 Excisional Surgery and Repair, Including Flaps and Grafts
Chapter 245 Mohs Micrographic Surgery
Chapter 246 Nail Surgery
Chapter 247 Cryosurgery and Electrosurgery
Chapter 248 Surgical Complications
Chapter 249 Wound Repair: Mechanisms and Practical Considerations
Chapter 250 Treatment for Varicose and Telangiectatic Leg Veins

Section 41. Cosmetic Dermatology
Chapter 251 Cosmetics and Skin Care in Dermatology
Chapter 252 Skin Resurfacing: Ablative Lasers, Chemical Peels, and Dermabrasion
Chapter 253 Cosmetic Applications of Non-Ablative Lasers and Other Light Devices
Chapter 254 Liposuction
Chapter 255 Soft-Tissue Augmentation
Chapter 256 Botulinum Toxin
Chapter 257 Hair Transplantation and Alopecia Reduction


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