HuGE Navigator

• January 29th, 2008

For information on population prevalence of genetic variants, gene-disease associations, gene-gene and gene- environment interactions, and evaluation of genetic tests, please look at the HuGE Navigator (http://www.hugenavigator.net/).

 
Thank you very much in advance for your contributions to this blog (Click on login to register and post a comment).

Click this link to see the most recent online abstracts of major genetics journals.

Philippe Campeau, MD
Resident in Medical Genetics at McGill University
OMMBID Blog Administrator

Hemochromatosis penetrance

• January 16th, 2008

This week, the New England Journal of Medicine publishes a study on the penetrance of HFE hereditary hemochromatosis. 31 000 individuals were studied in Australia. There were 203 C282Y homozygotes. Of these, 28% of the males and 1% of the females developed iron-overload-related diseases.

Read more at:
Iron-Overload–Related Disease in HFE Hereditary Hemochromatosis
KJ Allen, LC Gurrin, CC Constantine, et al.
NEJM Volume 358:221-230  January 17, 2008  Number 3

Editorial by BR Bacon and BS Britton

 
Thank you very much in advance for your contributions to this blog (Click on login to register and post a comment).

Click this link to see the most recent online abstracts of major genetics journals.
Philippe Campeau, MD
Resident in Medical Genetics at McGill University
OMMBID Blog Administrator